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Autoimmune Disease

Disease caused by breakdown of self-tolerance and subsequent immune response against self or autologous antigens, resulting in tissue injury, is called autoimmune disease. There are many theories to explain the development of autoimmune disease, and probably many mechanisms underlie the process. Autoimmune diseases can be caused by abnormal secretion of antibodies by activated B cells that bind to antigens in particular cells or by antigen-antibody complexes that form in the circulation and are then deposited in the blood vessel walls. Occasionally, T-lymphocytes may cause tissue injury either by directly killing target cells or by a delayed type of hypersensitivity reaction.

 

[Marrack P, Kappler J, Kotzin BL; Autoimmune disease: Why and Where it occurs. Nature Med 7: 899-905,2001].

Product links by technology :
Systemic autoantibodies
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IFA
ELISA
Organ specific autoimmunity
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PT. Inti Makmur Meditama
Gandaria 8 Office Tower
16 Floor Suite F
Jl. Sultan Iskandar Muda No. 8
Jakarta 12240 - Indonesia
T. +62 21 2930 3488 / 751 2786
F. +62 21 2930 3522 / 765 5230
Email. product.support@intimakmur.co.id / inmakmur@intimakmur.co.id


 

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